现代的纽约圣诞夜，当人们不再嘘寒问暖，五个素昧平生的人将会重新发现圣诞的真谛。杰拉找到勇气走出阴霾，亚提(亚伦阿金)悲剧的往事提醒了麦克珍惜眼前与妮娜(佩内洛普·克鲁兹)的关系，同时，萝丝(苏珊·萨兰登)找到了人生新希望，一段意想不到的友谊点醒了她，没有人在圣诞夜是真正孤独的……IntheChristmasEveinNewYork,thelonelydivorcedpublisherRoseHarrison(SusanSarandon)expectsforamiracletoimprovethehealthofhermother,internedinahospitalwithAlzheimer.Shefeelssorryforthepatientoftheroominfrontofhermother’sandmeetshisvisitor(RobinWilliams).Meanwhile,theLatinNinaVasquez(PenélopeCruz)breaksherengagementwithherbelovedfiancéMike(PaulWalker)duetohissuffocatingjealousy,butmisseshim.MikeisstalkedbythestrangerbartenderArtieVenzuela(AlanArkin).ThepoorJules(MarcusThomas)expectstospendtheChristmasnightinthehospital,wherehespentthebestChristmasofhislifewhenhewasateenager.Thelivesofsomeofthesecharacterscrosswithothersalongthenight.